1-(2-Hydroxyethyl)piperazine CAS 103-76-4 Purity >99.5% (GC) Factory High Quality

Short Description:

Chemical Name: 1-(2-Hydroxyethyl)piperazine

Synonyms: N-(2-Hydroxyethyl)piperazine; HEP 

CAS: 103-76-4

Purity: >99.5% (GC) 

Appearance: Colorless or Yellowish Liquid

Contact: Dr. Alvin Huang 

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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103-76-4 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 1-(2-Hydroxyethyl)piperazine (CAS: 103-76-4) with high quality. Ruifu Chemical has been supplying piperazines derivatives more than 15 years, can provide worldwide delivery, competitive price, small and bulk quantities available.
If you are interested in piperazines, Please contact: alvin@ruifuchem.com

103-76-4 - Chemical Properties:

Chemical Name 1-(2-Hydroxyethyl)piperazine 
Synonyms HEP; N-(2-Hydroxyethyl)piperazine; N-Hydroxyethylpiperazine; 1-Piperazineethanol; 1-Piperazineethanol; 2-(1-Piperazinyl)ethanol; Piperazine-1-Ethanol 
CAS Number 103-76-4
Stock Status In Stock, Production Capacity 200 Tons per Month
Molecular Formula C6H14N2O
Molecular Weight 130.19   
Melting Point -38.5℃(lit.) 
Boiling Point 246℃(lit.) 
Flash Point 124℃
Specific Gravity (20/20) 1.06
Refractive Index n20/D 1.51
Sensitive Hygroscopic. Air Sensitive 
Solubility in Water Completely Miscible With Water
COA & MSDS Available
Origin of Product Shanghai, China 
Product Categories Piperazines; Pharmaceutical Intermediates  
Brand Ruifu Chemical

103-76-4 - Specifications:

Item Specifications Results 
Appearance Colorless or Yellowish Liquid Conforms 
Purity / Analysis Method >99.5% (GC)   99.8% (GC) 
Specific Gravity (20/20℃) 1.060~1.063 1.060~1.063
Refractive Index n20/D 1.5055~1.5075  1.5055~1.5075
Water (by Karl Fischer) <0.30%  0.11%
Piperazine <0.10%  0.03%
Total Impurities <0.50%  0.20%
Infrared Spectrum Conforms to Structure  Conforms 
Test Standard Enterprise Standard  Conforms 

103-76-4 - Package/Storage/Shipping:

Package: Fluorinated bottle, 25kg/drum; 200kg/drum, or according to customer's requirement.
Storage Condition: Hygroscopic. Keep the container tightly closed. Store in a cool, dry and well-ventilated warehouse. Keep away from direct sunlight; avoid fire and heat sources; avoid moisture. Keep upright. Avoid violent collision. Light loading and unloading. 
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery. 

103-76-4 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

103-76-4 - FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Best quality, competitive price, professional services, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Custom SynthesisCan provide custom synthesis services.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

103-76-4 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes R36/37/38 - Irritating to eyes, respiratory system and skin.
R41 - Risk of serious damage to eyes
R38 - Irritating to the skin
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/39 -
S37/39 - Wear suitable gloves and eye/face protection
WGK Germany 1
RTECS TL6825000
TSCA Yes
HS Code 2942000000
Hazard Note Irritant 

103-76-4 - Application:

1-(2-Hydroxyethyl)piperazine (CAS: 103-76-4) is a hydroxyalkyl substituted pieprazine used in the preparation of pharmaceutical compounds.
1-(2-Hydroxyethyl)piperazine is used in organic synthesis, is a pharmaceutical intermediate, can be used to treat psychosis such as Fluphenazine.
1-(2-Hydroxyethyl)piperazine also can be used as an intermediate in the synthesis of Dasatinib (CAS: 302962-49-8) and Dasatinib Monohydrate (CAS: 863127-77-9). Dasatinib is an oral potent oncogenic kinase inhibitor, which can block signal of cancer cell replication acceleration , It has been clinically used for the treatment of various chronic myeloid leukemia (CML), including treatment of chronic myeloid leukemia which is resistant or intolerant to the treating programs including imatinib mesylate., Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL) and the treatment of patients with solid tumors.  

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